Banking Center Manager responsible for directing operational efforts and managing staff at a Prosperity Bank branch. Ensures compliance with policies while providing excellent customer service and managing profitability.
About the role
- Biomarker Clinical Assay Lead Manager role at Pfizer focusing on assay development and clinical strategy. Leading collaboration with internal and external partners in oncology.
Responsibilities
- Provide bio-analytical assay technical and operational expertise to Study Teams to ensure delivery of high-quality clinical biomarker and Diagnostic (Dx) data
- Support assay development, validation and timely availability of fit-for-purpose and Dx clinical biomarker assays to clinical Study Teams
- Function as key point of contact with external and internal clinical labs, with oversight responsibilities for agreements, work plans, budget and invoices, assay development, transfer, validation and associated report, sample analyses and associated report, data transfers and overall data quality
- Provide technical support for selection, qualification and periodic audits of bioanalytical laboratories supporting oncology clinical trial biomarker and Dx assays as appropriate
- Collaborate with Study Teams to ensure appropriate biomarker and Dx sample handling and processing steps are appropriately performed during clinical trials
- Serve as subject matter expert for biomarker and Dx testing technologies (NGS, PCR, IHC flow cytometry, immuno-assays etc)
- Collaborate with Asset Teams to manage the timely testing of clinical trial samples and the analysis and reporting of the associated data
Requirements
- PhD in a relevant scientific field (e.g. pathology, immunology, oncology, molecular biology, genetics) OR MS in a relevant scientific field (e.g. pathology, immunology, oncology, molecular biology, genetics) with 2+ years of relevant experience
- Experience with the research and development of biologic therapeutics, biomarker and Dx assay development, validation and execution in clinical trials
- Experience and expertise in biomarker selection trials
- Understanding of translational approaches as applied to clinical trial design and regulatory processes, proof-of-concept studies, and the implementation of biomarkers and Dx
- Development, validation, and implementation of a broad range of platform technologies within clinical trials (e.g. NGS, IHC, PCR, FISH, flow cytometry, other cell based and circulating biomarker technologies)
- Demonstrated understanding of clinical laboratory regulatory and compliance requirements (GLP, GCP, GCLP, CLIA, CAP)
- Demonstrated ability to think strategically and creatively while contributing to multiple projects simultaneously
- Experience working productively in a collaborative, multi-disciplinary and diverse team setting
- Excellent communication and organizational skills; able to convey complex scientific and business issues to devise, reach agreement on, and implement solutions
- Experience collaborating, leading, influencing, and motivating others
Benefits
- 401(k) plan with Pfizer Matching Contributions
- Additional Pfizer Retirement Savings Contribution
- Paid vacation
- Holiday and personal days
- Paid caregiver/parental and medical leave
- Health benefits including medical, prescription drug, dental and vision coverage
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