Hybrid Manager, Commercial Operations

at Karius

• Job title: Manager, Commercial Operations
• Job type: Full Time
• Experience level: Mid level, Senior
• Salary: $123,667 - $185,501 per year
• Degree requirement: Bachelor's Degree
• Location requirements: Hybrid, Redwood City, United States

About the role

• Manager of Commercial Operations at Karius optimizing commercial processes and infrastructure for advancing diagnostic solutions in infectious diseases.

Responsibilities

• Lead improvements to commercial processes and workflows across the go-to-market lifecycle (lead-to-opportunity-to-order-to-cash), ensuring clarity, consistency, and adoption.
• Partner with stakeholders to identify process gaps, define requirements, and deliver scalable solutions across CRM (Salesforce), marketing systems (HubSpot), and downstream integrations.
• Maintain governance of commercial master data (accounts, contacts, territories, referring institutions, attribution rules, etc.), including documentation and quality controls.
• Build and maintain process documentation, SOPs, and training materials to ensure consistency and enablement.
• Own the Commercial Ops intake and ticketing process (e.g., JIRA/other), including required fields, prioritization, assignment, and closure standards.
• Maintain clear SLAs (e.g., 48-hour response/turnaround where applicable), proactively communicating risks, dependencies, and timeline changes before deadlines slip.
• Maintain a transparent tracker/backlog for all workstreams and requests, including priority, owner, due date, dependencies, and next steps.
• Partner with the Commercial Operations leader to drive pipeline discipline, forecasting accuracy, and consistent inspection routines (weekly/monthly/quarterly).
• Support annual comp, quota/goal, and territory planning (analysis, scenarios, and execution) in partnership with the Commercial Operations leader.
• Own pipeline and funnel reporting, including stage definitions, conversion metrics, velocity, and leading indicators.
• Ensure consistent reporting definitions and governance, and maintain stakeholder trust in metrics and reporting.
• Develop and maintain dashboards and reporting that provide clear visibility into performance, pipeline, activity, and operational health.
• Design and develop complex queries, comprehensive reports, and analyses to facilitate fact-based business decisions.
• Perform business intelligence and analytics reporting to support commercial and field team initiatives.
• Translate analysis into decision support: succinct insights, implications (“so what”), recommendations, and execution next steps with owners and timelines.
• Create stakeholder-ready outputs (leadership updates, summaries, dashboards, and analyses) with minimal rework required.
• Establish reporting definitions, QA checks, and governance to ensure accuracy and stakeholder trust
• Support deal execution and deal desk processes as needed (quoting, approvals, routing, contracting coordination), ensuring accuracy and speed.
• Partner with Finance/Ops/Legal as appropriate to ensure contract and deal workflows are executed correctly and on time.
• Partner with Marketing and Sales to define and govern lead flow, handoffs, SLAs, attribution, and event ROI reporting by translating performance into clear recommendations for future investment.
• Drive enablement for commercial process changes by tailoring training and communications for a field audience to ensure adoption.

Requirements

• Bachelor’s degree required; graduate degree preferred.
• A minimum of 6-8 years of experience; Master’s degree with 4-6+ years of experience in Commercial Operations, Sales Operations, Revenue Operations, Business Operations, or related function in a high-growth environment.
• Extensive CRM and commercial systems experience (Salesforce and BI tools required; HubSpot, JIRA/Asana preferred).
• Proven ability to build scalable processes, governance, and operating rhythms across cross-functional stakeholders.
• Strong analytical skills with the ability to translate data into actionable business recommendations.
• Excellent project management and execution skills, including prioritization, tracking, dependency management, and on-time delivery.
• Proven ability to communicate with clarity and concision across levels, including senior leadership and field teams.
• High attention to detail with experience implementing QA controls and maintaining data integrity.
• Experience supporting healthcare, diagnostics, lab operations, or regulated environments.

Benefits

• Travel required up to 25%
• Health insurance
• Professional development opportunities