Hybrid Site Head – Chief Technology Officer, Manufacturing Operations

Posted last month

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About the role

  • Lead and oversee all operational activities across the batch production value chain for Cell and Gene Therapy products
  • Ensure facility, systems, and workforce are equipped, trained, and maintained to meet advanced biomanufacturing demands
  • Collaborate with department leads to ensure compliance with corporate, regulatory, and industry standards (GMP, ISO, etc.)
  • Drive site operations to achieve business goals, scale capacity, and meet growth strategies
  • Own site P&L, budget management, cost control, and financial performance
  • Build, develop, and retain high-performing teams; set performance standards and support career development
  • Monitor and report on operational metrics and KPIs; implement continuous improvement and lean practices
  • Ensure EH&S performance aligns with or exceeds industry best practices
  • Lead digital transformation integrating AI, automation, and robotics into manufacturing processes
  • Act as strategic leader representing the site internally and externally, including regulatory authorities and community
  • Provide strategic leadership in engineering and manufacturing technology; drive innovation and integration of AI, robotics, automation, and digital systems
  • Lead deployment of advanced automation solutions (physical robots and intelligent software) to improve efficiency and throughput
  • Develop and implement digital manufacturing ecosystem with real-time data collection, analysis, and visualization
  • Champion electronic batch records, MES, and paperless compliant batch documentation and traceability
  • Oversee remote monitoring systems for continuous insights into equipment, environmental conditions, and product status
  • Drive high-throughput production with rapid quality release emphasizing automation, workflows, and robust quality controls
  • Collaborate with CTOs for AI and IT to align manufacturing technology with organizational goals and ensure cybersecurity and integration
  • Partner with Quality, Regulatory, and Supply Chain to support compliance, data integrity, and validation requirements
  • Lead capacity planning and process optimization using data-driven insights
  • Develop metrics and KPIs related to automation, digital performance, and manufacturing efficiency
  • Serve as technical authority on smart manufacturing systems, system integration, cybersecurity, and data governance

Requirements

  • Bachelor's degree in Engineering, Biotechnology, or related technical field required
  • Advanced degree (Master’s or Ph.D.) in Engineering, Biotechnology, Bioengineering, Systems Engineering, or MBA preferred
  • Minimum of 15 years of progressive senior leadership experience in biopharmaceutical manufacturing (Cell and Gene Therapy/advanced biologics)
  • Proven track record of leading large-scale manufacturing facilities with full P&L responsibility
  • Extensive experience integrating AI, automation, robotics, and digital systems into GMP operations
  • Demonstrated expertise implementing electronic batch records, MES, remote monitoring, and real-time data analytics
  • Strong background in engineering management, process optimization, Lean/Six Sigma methodologies
  • Experience managing multidisciplinary teams across manufacturing, quality, engineering, facilities, supply chain, and regulatory
  • Familiarity with regulatory compliance (FDA, EMA, Health Canada) and GMP/ISO standards
  • Experience with capacity planning, scale-up, and commercial manufacturing of complex biologics and cell/gene therapies
  • Deep understanding of manufacturing automation, robotics, AI, data analytics, and cybersecurity for biomanufacturing
  • Experience with MES, ERP systems, electronic batch recording, and smart manufacturing principles
  • Proven leadership, strategic planning, stakeholder management, and change management skills
  • Applicants must be legally eligible to work in Canada

Job title

Site Head – Chief Technology Officer, Manufacturing Operations

Job type

Experience level

Lead

Salary

Not specified

Degree requirement

Bachelor's Degree

Location requirements

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