Hybrid Clinical Digital & AI Acceleration Portfolio Manager

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About the role

  • Clinical Digital & AI Acceleration Portfolio Manager leading digital transformation initiatives at Sanofi. Supporting strategic governance while ensuring measurable business and patient impact across clinical operations.

Responsibilities

  • Continuously align portfolio components with Sanofi’s strategy and CSO priorities
  • Shape and challenge the portfolio strategy by developing scenarios that support executive decision-making, trade-offs, and prioritization
  • Identify cross-initiative synergies, reuse opportunities, and integration levers to avoid siloed digital initiatives
  • Translate modernization ambitions (digital, data, AI) into executable, value-driven roadmaps
  • Actively identify new modernization opportunities across clinical operations, informed by performance data, capability gaps, and emerging technologies
  • Coordinate, evolve and professionalize the Initiative Portfolio Management Office (iPMO) as a strategic governance layer
  • Define and maintain governance standards covering value hypotheses, ROI tracking, adoption readiness, and scale-up criteria
  • Ensure alignment with Digital, eDEV, and CSO innovation governance
  • Monitor portfolio health using decision-grade performance intelligence
  • Partner with Finance and OPCM to drive disciplined investment management across the portfolio
  • Assess and consolidate portfolio-level resource needs, with a focus on critical capabilities rather than just capacity
  • Design and execute high-impact portfolio presentations, reports and communications for CSO leadership
  • Act as a trusted interlocutor for MPO leader and senior stakeholders, balancing competing priorities and perspectives

Requirements

  • Minimum 7+ years in project and portfolio management
  • Proven experience driving digital, data, or AI-enabled transformation in complex organizations
  • Strong command of portfolio governance, value-based prioritization, and performance tracking
  • Solid experience with business case development, ROI modeling, and financial steering
  • Demonstrated ability to partner with senior leaders and influence without direct authority
  • Experience in matrixed, global environments requiring orchestration across functions
  • Bachelors required. Master's degree or PhD preferred. Experience in digital audit is a plus.

Benefits

  • health insurance
  • prevention and wellness programs
  • at least 14 weeks’ gender-neutral parental leave

Job title

Clinical Digital & AI Acceleration Portfolio Manager

Job type

Experience level

SeniorLead

Salary

$148,500 - $214,500 per year

Degree requirement

Bachelor's Degree

Location requirements

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