Associate Director of Phenomics at GSK applying RWD and -omics for drug discovery. Leading complex analyses and advanced statistical approaches to support health outcomes research.
Responsibilities
Leverage longitudinal, RWD and other observational data derived from large, diverse human cohorts linked to genetics and other -omics to create novel, advanced phenotypes that describe disease severity, disease progression, disease sub-populations, biomarker trajectories, and more advanced health outcomes.
Proactively lead the design, delivery, and communication of custom analyses requiring advanced epidemiologic and/or statistical approaches to answer challenging scientific questions required for business development, portfolio decisions, or other GSK-critical requests where the integration of RWD with -omic data is an important component.
Advance novel methods ( e.g. AI/ML, mediation, interaction, other prediction, …) that improve our ability to develop novel phenotypes and analyses (as described above).
Identify and communicate the strengths, limitations, confounders, and potential biases for any downstream genetic or other -omic analyses that leverage inputs derived from RWD or other observational data.
Requirements
Advanced degree (PhD or equivalent) in a relevant scientific discipline.
Five or more years of experience in innovation and application of real-world data (RWD) and other observational data from large cohorts to answer diverse scientific questions across therapeutic areas.
Five or more years of experience in performing a range of statistical approaches supporting the analyses of identifying analytic cohorts, defining exposures, and measuring associations against diverse types of exposures and outcomes.
Three or more years of experience of delivering novel and impactful insights from complex EHR data individually, or through leadership of a team.
Three or more years of experience in R programming.
Three or more years of experience in Epidemiology and causal inference; demonstrated ability to apply advanced Epidemiology / causal inference to diverse datasets; and communicate methods and findings to a broad set of stakeholders.
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