BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases.
Millions worldwide are afflicted with genetic diseases, but small patient populations and industry reluctance to conduct early-stage development means that for many, treatments have not been forthcoming.
We are committed to bridging this gap: between business case and scientific possibility, between patient and hope.
BridgeBio creates a bridge from remarkable advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible.
BridgeBio is committed to developing leaders as well as drugs.
We are looking for individuals whose passion for creating life-changing medicines will inspire hands-on engagement and the dogged pursuit of novel solutions in the face of adversity.

BridgeBio

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manager

BridgeBio is a biotechnology company focused on designing transformative medicines for patients with genetic diseases. It employs a novel approach to drug development by integrating finance with science to deliver solutions as efficiently as possible. The company is committed to developing not only life-changing drugs but also leaders in the field, encouraging hands-on engagement and the pursuit of innovation. BridgeBio actively seeks investment to help achieve its mission of providing solutions for unique patient populations with unmet needs. Headquartered in Palo Alto, CA, BridgeBio emphasizes bridging the gap between scientific advancements and patient care.

BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases.

Millions worldwide are afflicted with genetic diseases, but small patient populations and industry reluctance to conduct early-stage development means that for many, treatments have not been forthcoming. We are committed to bridging this gap: between business case and scientific possibility, between patient and hope. BridgeBio creates a bridge from remarkable advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible.

BridgeBio is committed to developing leaders as well as drugs. We are looking for individuals whose passion for creating life-changing medicines will inspire hands-on engagement and the dogged pursuit of novel solutions in the face of adversity.

• Review of analytical data for release, stability, and in-process testing at the contract manufacturing organizations in a timely manner
• Oversight of laboratories including investigations for out of specification, out of trend, deviations, and/or anomalous results
• Follow up with the contract laboratories to correct any deficiencies/omissions in the provided test packages
• Submitting test packages to QA for their review and loading all data into the electronic storage program
• Review of analytical data related to reference standard qualification, method validation and method transfer activities
• Travel, when necessary, to analytical testing sites or other sites
• Able to communicate results both internally and externally through oral and written updates and formal reports as necessary
• Create or review BBio Standard Operating Procedures as it pertains to Quality Control or management of contract analytical laboratories

Quality Control Manager

Manager of Quality Control ensuring compliance with cGMP in pharmaceutical settings. Overseeing analytical data and collaborating with contract labs at BridgeBio Pharma.

director

• Director of Drug Safety will be responsible for managing all aspects of the drug safety functions related to US and assigned postmarketing data review and reporting.
• Manage the drug safety contract service organizations (CSOs) for postmarket pharmacovigilance with >=95% compliance with periodic reporting, signal management, and global risk management plans and, manage on-time and scientifically sound local safety report preparation, and ensure the drug safety functions of the CSOs meet corporate goals and key performance indicators
• Develop and prepare assessments of global safety data, signal management, and benefits/risks for internal senior management as well as external partner or regulatory authorities
• Accountable for global periodic safety review and signal management meetings, and relationships with all internal and external stakeholders, and maintain audit trail as inspection ready at all times
• Accountable for maintenance and inspection readiness of the quality management system for signal management (GVP Module IX.B.5) and PBRER preparation
• Leads data collection for signal examination and assessment within timelines
• Accountable for ad hoc safety review meetings, including all internal and external stakeholders, with 100% compliance with signal evaluation timelines, and maintain audit trail as inspection ready at all times
• Manages the authoring of aggregate reports including PBRER, and other local safety reports as required
• Manages the authoring and collaboration with partner for global risk management plans
• Manages the PV agreements and compliance of all assigned local distribution organizations and for compliance tracking for all safety submissions across all drug safety functions of the local distribution organizations, maintain audit trail as inspection ready at all times
• Oversee the creation of periodic report and signal management reports, analysis, and presentation of safety data from the safety database, and maintain audit trail as inspection ready at all times
• Manages ongoing reconciliation of incoming safety information and the safety databases
• Develops and prepares reports for company management as well as external regulatory agencies
• Ensure compliance with standard operating procedures and clinical trial and post-market global drug safety regulations, including to the FDA, EMA, MHRA, and all assigned international RAs
• Implement pharmacovigilance SOPs and ensure the uniform and timely processing of adverse event data in all assigned development and post-marketing programs
• When requested, work with other BridgeBio Affiliates to provide strategic input and work on assigned non-product/compound-related projects

Director, Drug Safety – Pharmacovigilance

Director of Drug Safety at BridgeBio Pharma responsible for post-market safety functions and compliance. Overseeing drug safety operations and reporting with a focus on regulatory compliance.

operations

• The successful candidate will report to the SVP, Head of International and partner with Medical Affairs, Market Access and the BridgeBio leadership/corporate stakeholders.
• This role will build regional readiness across all aspects of commercialization and business performance: Strategy, launch preparation, tactical execution and operational excellence while delivering on established KPIs.
• Define and lead the International Commercial Operations strategy aligned with BridgeBio International objectives.
• Build out and lead a best-in-class team across the International Region to support launches of current and new products into the marketplace.
• Drive launch readiness across multiple geographies, ensuring flawless execution of pre- and post-launch activities.
• Partner with Global, Regional and Local teams to ensure strategic alignment while adapting approaches to local market dynamics.
• Establish best-in-class launch frameworks, operating models, and governance processes to accelerate time-to-market.
• Design and implement KPI dashboards and reporting systems to track performance, provide actionable insights, and drive accountability.
• Continuously optimize commercial operations, ensuring agility, efficiency, and scalability across diverse markets.
• Shape the design and deployment of customer-facing organizations across international markets, ensuring optimal structure, size, and capability.
• Oversee training, tools, incentives and capability-building programs that enhance field productivity and patient impact.
• Champion a customer-centric approach, ensuring frontline teams are empowered to deliver value across the patient journey.
• Lead the generation and integration of market insights, including patient journey mapping, segmentation, and competitive analysis.
• Translate insights into actionable strategies that address unmet needs and drive market adoption.
• Anticipate external trends, regulatory shifts, and access dynamics to inform proactive commercial planning.
• Act as a key partner to Medical Affairs, Market Access, Regulatory, and Corporate leadership to ensure integrated execution.
• Build and maintain strong relationships with Key Opinion Leaders, industry stakeholders, and partners to shape markets and advance patient access.
• Cultivate a high-performance culture that emphasizes collaboration, accountability, and innovation across the International business.

VP, Commercial Operations – International

VP, Commercial Operations leading international strategies for BridgeBio Pharma. Reporting to SVP and partnering with cross-functional teams to drive commercialization and operational excellence.

• Lead and design comparative effectiveness and health outcomes studies using real-world data (RWD), registries, claims databases, and clinical data sources
• Develop strategic evidence plans that address clinical, payer, and patient stakeholder needs
• Apply advanced study designs (e.g., propensity score matching, instrumental variables, target trial emulation) to generate credible, high-impact insights
• Collaborate cross-functionally with Clinical Development, Health Economics and Outcomes Research (HEOR), Market Access, and Data Science teams to align evidence strategies with organizational priorities
• Communicate findings in scientific forums, peer-reviewed publications, and internal stakeholder briefings
• Serve as a subject matter expert in comparative effectiveness research within Medical Affairs
• Represent the company in external collaborations, advisory boards, and industry working groups focused on RWE and methodological innovation
• Provide mentorship and scientific guidance to evidence scientists and cross-functional partners

Senior Director, Evidence Generation

Senior Director of Evidence Generation working with the Evidence Generation team at BridgeBio Pharma. Focused on comparative effectiveness research and health outcomes innovation for rare diseases.

BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases. Millions worldwide are afflicted with genetic diseases, but small patient populations and industry reluctance to conduct early-stage development means that for many, treatments have not been forthcoming. We are committed to bridging this gap: between business case and scientific possibility, between patient and hope. BridgeBio creates a bridge from remarkable advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible. BridgeBio is committed to developing leaders as well as drugs. We are looking for individuals whose passion for creating life-changing medicines will inspire hands-on engagement and the dogged pursuit of novel solutions in the face of adversity.

BridgeBio

About the company

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16 jobs found

Quality Control Manager

BridgeBio

Director, Drug Safety – Pharmacovigilance

BridgeBio

VP, Commercial Operations – International

BridgeBio

Senior Director, Evidence Generation

BridgeBio