Hybrid Director, Clinical Imaging – Respiratory & Immunology

Posted 7 hours ago

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About the role

  • Lead imaging strategy and execution for clinical projects in respiratory and immunology at AstraZeneca. Drive cross-program initiatives and coordinate with data science for optimal outcomes.

Responsibilities

  • Define and lead the cross-program imaging strategy for assigned assets; translate disease biology into actionable imaging endpoints and decision points in the Clinical Development Plan (CDP)
  • Serve as the imaging voice on Global Project Teams and Clinical Program Teams, influencing asset strategy and investment
  • Lead selection, technical validation, and qualification of imaging endpoints (standard and exploratory), including modality/sequence selection, acquisition/reconstruction parameters, site readiness, and harmonization plans
  • Lead all aspects of imaging protocol build, imaging charters, manuals, and risk-based quality management
  • Partner with data science/biometrics to develop data flows (from DICOM to analysis-ready formats), ensure metadata completeness, and apply sophisticated analytics (e.g., radiomics, ML/AI, deep learning, quantitative segmentation)
  • Select and lead imaging CROs, core labs, and image analysis vendors; supervise technical performance and data quality
  • Anticipate and address regulatory expectations for imaging endpoints; contribute to interactions, submissions, and responses, including documentation of imaging methods, validation packages, and sensitivity analyses.
  • Present imaging strategies and readouts to governance and senior partners.

Requirements

  • At least 5+ years of experience with a Doctoral degree in an imaging-related field (PhD and/or MD) or equivalent sophisticated training
  • strong grounding in clinical imaging modalities, preferably CT and MRI, with strong understanding of acquisition and analysis
  • Consistent track record leading imaging endpoints in Phase I–IV trials, including develop, operationalization, and delivery in multicenter settings
  • Practical experience in quantitative image analysis and image informatics, including familiarity with DICOM standards, curation, harmonization, and quality control
  • Shown ability to analyze and interpret large, multimodal datasets (e.g., imaging + clinical + biomarkers/omics); experience working with statisticians and data scientists to build pre-specified analysis plans and validate algorithms
  • Strong cross-functional leadership and influence skills; success working in fast-paced, matrixed environments and driving decisions at asset and program governance
  • Excellent written and verbal communication, with the ability to translate sophisticated imaging and analytics concepts to diverse partners.

Benefits

  • health benefits including medical, prescription drug, dental, and vision coverage
  • short-term incentive bonus opportunity
  • eligibility to participate in our equity-based long-term incentive program (salaried roles)
  • retirement contribution (hourly roles)
  • paid vacation and holidays
  • paid leaves

Job title

Director, Clinical Imaging – Respiratory & Immunology

Job type

Experience level

Lead

Salary

$249,827 - $374,741 per year

Degree requirement

Postgraduate Degree

Location requirements

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