Hybrid Associate Director, Statistical Pharmacogenetics

at GSK

• Job title: Associate Director, Statistical Pharmacogenetics
• Job type: Full Time
• Experience level: Senior
• Salary: Not specified
• Degree requirement: Postgraduate Degree
• Tech skills: Python
• Location requirements: Hybrid, Upper Providence, United States

About the role

• Associate Director, Statistical Pharmacogenetics at GSK, conducting analyses on clinical trial data. Collaborating across teams to deliver pharmacogenetic insights in the development process.

Responsibilities

• Conduct hands-on pharmacogenetic analyses of clinical trials
• Design and author statistical analysis plans and pharmacogenetic reports
• Collaborate and work closely with colleagues in cross-functional teams to oversee the development and timely delivery of pharmacogenetic analyses and reports
• Perform a range of statistical genetic analyses including, but not limited to, power calculations, single variant tests, burden tests, and polygenic risk scores
• Integrate genetics and other omics data in analyses to gain novel translational insights
• Understand the strengths and limitations of different statistical genetic analyses for pharmacogenetics
• Evaluate and implement new methodologies and technologies to improve the efficiency and effectiveness of genetic analyses
• Ensure compliance with relevant regulations and guidelines in the field of pharmacogenetics.

Requirements

• PhD or equivalent advanced degree in a relevant scientific discipline (e.g. statistical genetics, genetic epidemiology, biomedical statistics, computational sciences, bioinformatics)
• Expertise in statistical genetics
• Experience of conducting genetic analyses of clinical trial data
• Strong written communication skills to design and write pharmacogenetic statistical analysis plans and reports
• Strong proficiency in at least one of R and Python, with experience of writing reproducible and scalable code that abides to FAIR principles
• Excellent collaboration and partnership skills to work effectively with internal stakeholders across functions
• Demonstrated experience of effectively communicating complex scientific concepts to diverse audiences
• Demonstrated ability to work effectively both independently and in multidisciplinary teams to meet project timelines.

Benefits

• Professional development opportunities
• Flexible working hours