Hybrid Senior Scientist II, Applied Machine Learning, Translational Agentic AI

Posted 44 minutes ago

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About the role

  • Senior Scientist II leading innovative AI and machine learning projects in oncology at Tempus. Collaborating with teams to advance predictive modeling and drug R&D initiatives.

Responsibilities

  • Lead the scientific development of cutting-edge agentic frameworks for oncology
  • Architect sophisticated "deep agents" for hypothesis generation, experimental design, and multimodal ML and AI modeling
  • Innovate scientific methodology by developing new predictive models and causal inference frameworks
  • Work with Research, Engineering & Data Science teams to develop innovative computational solutions
  • Collaborate with clinical scientists and pharma partners to define high-value use cases

Requirements

  • Minimum PhD (or Masters degree with 5+ years of relevant experience)
  • 2+ years of relevant industry or post-doctoral experience involving medicine and AI
  • Quantitative and computational skills in AI agent based workflows (e.g. Applied Machine Learning, Generative AI, Mathematics, biostatistics)
  • Biological, medical, translational or drug development knowledge and data (e.g. oncology, RWE, medical science, or clinical drug development)
  • Expert-level proficiency in Python and orchestration frameworks, specifically LangGraph or similar
  • Experience building deep agents with complex state management and graphs
  • Deep knowledge of prompt engineering, RAG (Retrieval-Augmented Generation), function calling, and evaluating non-deterministic LLM outputs
  • Strong foundation in survival analysis (CoxPH, RSF, NN) and evaluation metrics for oncology models
  • Experience working with clinical trial or real-world data, clinical guidelines
  • Track record of success in peer-reviewed publications or proven impact

Benefits

  • incentive compensation
  • restricted stock units
  • medical and other benefits depending on the position

Job title

Senior Scientist II, Applied Machine Learning, Translational Agentic AI

Job type

Experience level

Senior

Salary

$125,000 - $185,000 per year

Degree requirement

Postgraduate Degree

Tech skills

Location requirements

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