Onsite Principal Scientist – In Vivo Pharmacology

Posted 2 days ago

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About the role

  • Principal Scientist leading obesity and diabetes research at Novo Nordisk. Conducting in vivo pharmacology studies and collaborating across teams to advance therapeutics.

Responsibilities

  • Lead scientific excellence in obesity and diabetes research to advance target discovery, innovation, and project progression.
  • Design and conduct pivotal in vivo experiments to assess pharmacokinetics, pharmacodynamics, efficacy, safety signals, and mechanism-of-action by applying state‑of‑the‑art tools.
  • Develop, optimize, and implement new disease‑relevant models and methods to evaluate biological activity of new targets and modalities.
  • Develop study protocols; analyse and interpret data; ensure rigorous documentation; report findings; excellent in project management and clearly communicate results to project teams, governance boards, and Global Research leadership.
  • Collaborate closely within a matrix environment—partnering with internal teams, external CROs, scientific advisors, and academic centres of excellence—to deliver high-quality, decision-enabling data.
  • Mentor, coach, and develop junior scientists; foster a culture of scientific rigor, innovation, and accountability.

Requirements

  • PhD in pharmacology, physiology, endocrinology, metabolism or related field, with significant experience; preferably 5-10 years in pharma/biotech R&D.
  • Experience in rodent obesity and Type 2 diabetes pharmacology, including hands-on study design and execution to assess body weight, food intake, energy expenditure, and body composition; familiarity with translational endpoints and model limitations is a strong plus.
  • Experience advancing drug candidates in obesity or related cardiometabolic indications into development, with strong publication record and evidence of impactful decision‑making is advantageous.
  • Experience of working with different therapeutic modalities and with combination strategies targeting complementary pathways will be a clear advantage.
  • Experience leveraging data to guide decisions, working with digital tools, and collaborating with bioinformatics teams.
  • Excellent collaboration, team player spirit, clear communication, and problem‑solving skills; fluent in written and spoken English.

Benefits

  • Health insurance
  • Professional development opportunities

Job title

Principal Scientist – In Vivo Pharmacology

Job type

Experience level

Lead

Salary

Not specified

Degree requirement

Postgraduate Degree

Location requirements

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