Principal Scientist leading DMPK strategy for drug discovery programs at Novo Nordisk. Engaging in cross-functional collaboration and managing research initiatives for therapeutic areas.
Responsibilities
Provide scientific leadership in the discovery of small molecule drug candidates
Define and drive internal and external research initiatives that support program milestones
Propose experimental and modeling approaches to de risk projects and advance molecules with drug like properties
Lead DMPK efforts to optimize candidates using in vitro, in vivo and in silico methods
Manage CRO relationships with specialized ADME capabilities in collaboration with outsourcing managers
Engage with global Novo Nordisk ADME experts to harmonize strategy and leverage best practices
Provide scientific mentorship and technical leadership to DMPK team members and cross functional colleagues
Communicate DMPK strategy, findings and risk assessments clearly to project teams and senior management
Represent the company externally as needed to build visibility for DMPK methods and capabilities
Requirements
Bachelor's degree with 18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree with 6+ years’ post-doctoral and/or industry relevant experience
Excellent understanding of small molecule ADME principals
Hands on experience with PK and PK/PD modeling or biotransformation highly desirable
Preferred experience includes DMPK or PK/PD modeling project representation for small molecule projects
Excellent verbal and written communication skills
Benefits
Medical, dental and vision coverage
Life insurance
Disability insurance
401(k) savings plan
Flexible spending accounts
Employee assistance program
Tuition reimbursement program
Voluntary benefits such as group legal, critical illness, identity theft protection, pet insurance and auto/home insurance
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