Kyverna Therapeutics is a clinical-stage cell therapy company with the mission of engineering a new class of therapies for autoimmune and inflammatory diseases.
The Kyverna therapeutic platform combines advanced T cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases.
Kyverna’s pipeline includes KYV-101, a fully human, autologous chimeric antigen receptor (CAR) T-cell therapy with properties well suited for use in B cell-driven autoimmune diseases and KYV-201, a fully human, allogeneic CAR T-cell therapy.
By offering more than one mechanism for taming autoimmunity, and with patients currently in treatment for multiple indications in the U.S.
and Europe, Kyverna is positioned to act on its mission of transforming how autoimmune diseases are treated.

Kyverna Therapeutics

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accounting-manager

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The company is pioneering CAR T-cell therapies, leveraging the transformational power of T cells to potentially provide sustained, treatment-free remission for autoimmune conditions. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through clinical trials targeting various autoimmune diseases, including multiple sclerosis, myasthenia gravis, systemic sclerosis, and lupus nephritis. Their pipeline features innovative chimeric antigen receptor (CAR) T-cell therapies in both autologous and allogeneic formats aimed at B cell-driven autoimmune diseases.

Kyverna Therapeutics is a clinical-stage cell therapy company with the mission of engineering a new class of therapies for autoimmune and inflammatory diseases. The Kyverna therapeutic platform combines advanced T cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases. Kyverna’s pipeline includes KYV-101, a fully human, autologous chimeric antigen receptor (CAR) T-cell therapy with properties well suited for use in B cell-driven autoimmune diseases and KYV-201, a fully human, allogeneic CAR T-cell therapy.  By offering more than one mechanism for taming autoimmunity, and with patients currently in treatment for multiple indications in the U.S. and Europe, Kyverna is positioned to act on its mission of transforming how autoimmune diseases are treated. 

• Lead the month-end, quarter-end, and year-end financial close processes
• Own the general accrual process, including contract review and preparation of journal entries
• Manage and oversee end-to-end Accounts Payable operations, providing leadership to an offshore AP team
• Oversee lease accounting activities in accordance with ASC 842
• Maintain and reconcile fixed asset schedules
• Manage the corporate card program
• Monitor and amortize prepaid expenses
• Oversee cash and investment account reconciliations
• Support other Associate Directors of Accounting and provide accounting support for CRO and/or CMO accruals
• Own SOX control execution and documentation for assigned accounting areas
• Prepare audit schedules and financial analytics

Associate Director, Accounting

Associate Director of Accounting at Kyverna Therapeutics leading month-end close and overseeing Accounts Payable operations. High-impact role in a clinical-stage biopharmaceutical company.

director

• Establish and lead GCP/GLP/GPV efforts
• Have clinical quality compliance oversight for clinical development programs both in the US and internationally
• Collaborate with internal clinical and nonclinical functions and external parties including consultants, contract auditors, CROs and investigator sites to promote a high level of quality and consistency across and within programs
• Develop the risk-based audit and compliance strategy for all programs
• Independently manage domestic and international risk-based audits of investigator sites, study documents, databases, vendors, partners, and internal systems in compliance with GCP, GLP, and Company policies and procedures
• Assess impact of audit findings on subject safety, data integrity, and business operations
• Support a culture of sustainable compliance; assist project teams in implementing corrective and preventive actions

Director, Clinical Quality

Director of Clinical Quality in a biopharmaceutical company developing cell therapies. Leading GCP/GLP compliance and clinical oversight for development programs in the US and internationally.

affiliate-manager

• Own the strategy, delivery, and ongoing optimization of Finance, Accounting, Legal, HR, and Commercial systems to support business growth, operational efficiency, and regulatory compliance.
• Document, analyze, and continuously improve end-to-end business processes and workflows, identifying opportunities for automation and reduction of manual activities.
• Partner closely with functional leaders to understand business needs and translate them into system solutions, including development of business cases, cost-benefit analyses, and ROI assessments for new implementations or enhancements.
• Lead the full system lifecycle from intake and vendor selection through implementation, validation, go-live, and post-launch support, including requirements gathering, configuration, SOX validation, testing, training, and stabilization.
• Establish and manage change control processes and lead system upgrades, patches, and enhancements to ensure system reliability, security, and compliance.
• Champion IT governance by driving consistent application of policies, procedures, and best practices across all G&A systems.
• Ensure the accuracy, completeness, and integrity of SOX-relevant data through system controls, audits, and reconciliations.
• Develop and deliver dashboards, reports, and analytics that provide leadership with clear insights into business performance, system health, and operational KPIs.
• Ensure all supported systems comply with applicable regulatory and privacy requirements, including FDA regulations, GDPR, and other biotech and life sciences standards.
• Develop, maintain, and audit system validation and SOX documentation.
• Implement and enforce security controls to protect sensitive information, including patient data, employee records, and proprietary research.
• Act as an escalation point and hands-on problem solver for critical G&A system issues, balancing strategic leadership with operational execution.
• Collaborate with IT leadership and business stakeholders to define and maintain a cross-functional G&A systems roadmap aligned with corporate priorities.

IT G&A Business Partner

IT G&A Business Partner at Kyverna Therapeutics managing systems for Finance and HR functions. Transforming the future of treatment for autoimmune diseases in a regulated biotech environment.

• Provides enterprise-level strategic and operational leadership for Quality Control activities supporting both development and commercial programs.
• Serves as the primary point of accountability for QC oversight across the organization, including outsourced testing networks, stability programs, regulatory submissions, and global inspection readiness.
• Partners closely with Technical Development, Quality Assurance, Regulatory Affairs, and other cross-functional stakeholders to ensure compliance with global regulatory requirements while enabling efficient pipeline advancement and commercial execution.
• Responsible for building and sustaining a scalable, inspection-ready QC organization.
• Drives continuous improvement across the quality system, provides strategic input into program and manufacturing decisions, and represents QC to the executive level.
• Has significant influence on regulatory outcomes, operational performance, and the overall credibility of the company’s quality function.

Director, Quality Control

Leading Quality Control operations for biopharmaceutical company Kyverna Therapeutics. Overseeing compliance and strategic leadership in cell therapy development and commercialization.

vice-president

• Build and Lead the Global Quality organization, ensuring proper and effective quality oversight and governance for all GxP disciplines across internal and external operations.
• Establish and uphold global quality standards for cell therapy programs, ensuring alignment with health authority requirements and industry best practices.
• Ensure product submissions, product performance, and compliance concerns are adjudicated in an effective way that is commensurate with prevailing and emerging regulatory expectations and in line with established Standards and Policies.
• Serve as an integral member of Kyverna executive management, contributing to corporate and functional strategy. Building cross-functional relationships and representing the Quality function and quality standards on program and strategy teams.
• Ensure Quality is a strategic enabler of innovation, resource prioritization, effective risk management in line with the corporate phase of operations.
• Maintain expert, up-to-date knowledge of international GxP regulations and guidance. Serve as Kyverna’s primary point of contact with Health Authority inspectorates, leading global inspections, audits, and inspection-readiness initiatives.
• Design and implement robust, risk-based quality management systems and operations that ensure compliance across clinical trial execution, development, manufacturing, testing, and logistics operations. Develop escalation frameworks for timely and robust issue communication, management and resolution.
• Provide Quality oversight for international clinical trials, technical operations and external engagement, including due diligence, qualification, and ongoing management of Contract Manufacturing, Contract Research Organizations, and Strategic Partners. Ensure alignment with evolving regulatory expectations for cell and gene therapy products.
• Provide decisive leadership for significant compliance events, deviations, or product issues that could affect patient safety or business continuity, ensuring timely communication and effective mitigation.
• Provide strategic leadership for Inspection Readiness including vendor selection and oversight, planning and training of all cross-function team members, and preparation for inspections including key vendors and investigator sites.
• Build, mentor, and empower a high-performing Quality team with clear accountability, efficient decision-making, and an unwavering commitment to excellence.
• Partner closely with R&D, Manufacturing, Regulatory, and Commercial leaders to ensure cohesive implementation of Quality policies and timely resolution of quality-related matters.
• Represent Kyverna in global industry forums, scientific boards, and regulatory working groups to influence and shape evolving standards in cell and gene therapy regulation.

VP, Quality

VP leading global Quality functions across biopharmaceutical operations. Developing and maintaining GxP Quality frameworks to ensure compliance and patient safety.

Kyverna Therapeutics is a clinical-stage cell therapy company with the mission of engineering a new class of therapies for autoimmune and inflammatory diseases. The Kyverna therapeutic platform combines advanced T cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases. Kyverna’s pipeline includes KYV-101, a fully human, autologous chimeric antigen receptor (CAR) T-cell therapy with properties well suited for use in B cell-driven autoimmune diseases and KYV-201, a fully human, allogeneic CAR T-cell therapy. By offering more than one mechanism for taming autoimmunity, and with patients currently in treatment for multiple indications in the U.S. and Europe, Kyverna is positioned to act on its mission of transforming how autoimmune diseases are treated.

Kyverna Therapeutics

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5 jobs found

Associate Director, Accounting

Kyverna Therapeutics

Director, Clinical Quality

Kyverna Therapeutics

IT G&A Business Partner

Kyverna Therapeutics

Director, Quality Control

Kyverna Therapeutics

VP, Quality

Kyverna Therapeutics