Senior Manager Data Scientist working on innovative drug development in a cutting-edge team at Bristol Myers Squibb. Focused on computational methods for patient segmentation and biomarker strategy.
Responsibilities
Develop and apply novel or existing computational methods for patient segmentation from multimodal clinical and omics datasets for various treatment modalities in partnership with Translational, Clinical and Statistical Scientists.
Partner with lead and protocol statisticians in writing, reviewing and executing protocols and statistical analysis plans (SAP) for biomarkers and diagnostics, highlighting the biomarker strategy for clinical drug development.
Execute biomarker analyses on datasets from BMS clinical trials and real-world data cohorts.
Perform relevant and innovative statistical analyses of high-dimensional (e.g. gene expression, sequencing) data generated by cutting edge technologies.
Execute and contribute to the scientific and statistical strategy of drug development, including development of predictive biomarker(s) and precision medicine.
Optimize and validate biomarker assays for clinical trial usage.
Develop, implement, and apply state-of-the-art algorithms to address key business problems and drive the implementation of innovative statistical methods in support of biomarker strategy.
Formulate, implement, test, and validate predictive models and implement efficient automated processes for producing modeling results at scale.
Responsible for collaborating with cross-functional teams, including but not limited to clinicians, data scientists, translational medicine scientists, statisticians, and IT professionals.
Manage and coordinate resources to produce quality deliverables within timelines for competing priorities.
Requirements
Ph.D. in a relevant quantitative field (i.e. Computational Biology, Biostatistics, Statistics, Computer Science, etc.) and 1+ years of academic/industry experience or Master’s Degree in a relevant quantitative field and 3+ years of industry experience.
Strong experience in the analysis of data generated by one or more -omics or molecular assays is required.
Knowledge of molecular biology, understanding of disease pathways are preferred.
Strong experience in biomarker data analysis with data generated from clinical trials, or electronic health records.
Experience in modeling methods particularly in their application to pharma R&D.
Experience in the application of AI/ML, and proficient in SQL, Python, and R and cloud platforms.
Experience developing statistical and machine learning models on high dimensional and high throughput data for time to event data and longitudinal outcomes.
Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.
Strong problem-solving and collaboration skills, and rigorous and creative thinking.
Excellent communication, data presentation, and visualization skills.
Benefits
Medical, pharmacy, dental and vision care.
Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
Financial well-being resources and a 401(K).
Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
Parental, caregiver, bereavement, and military leave.
Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
Other perks like tuition reimbursement and a recognition program.
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