Hybrid Technical Program Manager, Sequencing, Science

at Chan Zuckerberg Initiative

• Job title: Technical Program Manager, Sequencing, Science
• Job type: Full Time
• Experience level: Senior, Lead
• Salary: $153,000 - $210,000 per year
• Degree requirement: Bachelor's Degree
• Location requirements: Hybrid, Redwood City, United States

About the role

• Senior Technical Program Manager ensuring reliable and secure sequencing data integration into CZI's ecosystem. Leading cross-functional efforts to deliver compliant datasets for innovative biological modeling.

Responsibilities

• Drive cross-functional programs to ingest, manage, and serve large-scale sequencing datasets, ensuring timely, secure, and accurate delivery.
• Collaborate with platform scientists generating data to align on scope, timelines, and quality expectations.
• Partner with infrastructure and data engineers to build scalable, reliable ingestion pipelines that meet regulatory and security requirements.
• Work with data scientists to codify data quality and format standards, enabling seamless downstream use for model training.
• Manage complex stakeholder relationships across internal teams, CROs, and grantees to ensure successful data delivery.
• Establish program structures, roadmaps, and milestones that drive accountability and progress across teams.

Requirements

• 8+ years of experience in technical program management or related roles, with demonstrated success leading large-scale, cross-functional initiatives.
• Familiarity with genomics and sequencing data modalities (e.g., scRNA-seq, WGS) and their unique challenges in scale, quality, and compliance.
• Experience managing programs with regulatory or data security requirements, ideally in a biological or healthcare context.
• Proven ability to coordinate across engineering, scientific, and research stakeholders to deliver complex technical outcomes.
• Strong organizational, communication, and leadership skills, with the ability to bring clarity and momentum to ambiguous and multi-stakeholder environments.
• Enthusiasm for working in a multidisciplinary environment spanning biology, data, and AI research, and for learning new domains quickly.

Benefits

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
• Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them.
• Paid time off to volunteer at an organization of your choice.
• Funding for select family-forming benefits.
• Relocation support for employees who need assistance moving to the Bay Area