Hybrid Human Genomics and Translational Data Sciences

Posted last month

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About the role

  • Provide scientific leadership and strategic vision in human genetics, proteomics, population data science, and clinical informatics to position Lilly at the forefront of genetics for diabetes, obesity, and complications
  • Lead and mentor a team with diverse computational background
  • Develop and implement strategies to optimally use public large-scale genetic/genomic resources (population-scale biobanks, genome sequencing initiatives) and integrate with patient-derived data from clinical trials to provide novel insights for Lilly’s portfolio
  • Lead efforts to analyze whole genome sequencing and proteomics data from clinical trial participants
  • Align with DOCTA’s strategic priorities and drive data-driven innovative approaches to identify and validate novel therapeutic targets
  • Spearhead cross-functional initiatives to translate genetic/genomic findings into actionable insights that inform drug discovery, biomarker development, and clinical trial design
  • Represent Lilly at scientific conferences and engage with the broader genetics/genomics community to stay at the forefront of innovation
  • Partner with internal teams to evaluate external innovation opportunities and bring insights to aid decision making
  • Interpret and clearly communicate results from genetic analyses, including development of scientific manuscripts, posters, and presentations; communicate the group’s vision and progress to internal and external partners
  • Implement industry-standard procedures for scientific project execution and documentation (e.g., JIRA, Confluence, Git, code review, and other documentation tools)
  • Accountable for the team’s development and documentation of reproducible pipelines for genetics analyses
  • Perform hands-on execution of human genetic analyses as needed
  • Foster a culture of scientific excellence, collaboration, and continuous learning within the human genetics and bioinformatics group and across the organization

Requirements

  • PhD or equivalent in Human Genetics, Epidemiology, Clinical Informatics, or related field with at least 5 years in a leadership role; MD + PhD preferred
  • Demonstrated success in building, mentoring, and managing scientific teams (3+ years managing direct reports required)
  • Led or played a significant role in high-impact research programs in pharma, biotech, or academia; knowledge of drug development strongly preferred
  • Prior experience with multiple in human genetics workflows including analysis of WGS, WES, and genotyping data for association analyses, polygenic risks score analysis, and analysis of rare variants, required
  • Prior experience working with clinical and observational biomedical informatics data sets, including data from clinical trials, EHRs, and large biobanks (e.g., UKBB), required
  • Prior experience with clinical/diagnostic genetics, including application of ACMG criteria for annotation of variant pathogenicity, strongly preferred
  • Strong track record of publications in top-tier journals
  • Strong collaborative approach with outstanding communication and interpersonal skills to engage cross-functional teams and external partners
  • Ability to prioritize and manage multiple competing priorities within a fast-paced environment
  • Demonstrated ability to lead and manage successfully within a matrixed organization
  • Strongly team-oriented with a customer focused design thinking mentality

Benefits

  • Eligibility to participate in a company-sponsored 401(k)
  • Pension
  • Vacation benefits
  • Eligibility for medical, dental, vision and prescription drug benefits
  • Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
  • Life insurance and death benefits
  • Certain time off and leave of absence benefits
  • Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

Job title

Human Genomics and Translational Data Sciences

Job type

Experience level

Mid levelSenior

Salary

$184,500 - $321,200 per year

Degree requirement

Postgraduate Degree

Location requirements

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