Director leading healthcare solutions for Genentech in Texas and Oklahoma. Focused on delivering patient outcomes and managing a diverse team to meet business objectives.
About the role
- Director/Senior Director at Lilly overseeing ADMET & PK/PD modeling initiatives for drug discovery. Focus on predictive models and translational approaches in the biotech ecosystem.
Responsibilities
- Build and validate predictive models across key ADMET and PK/PD endpoints.
- Develop translational modeling approaches to generate actionable predictions for biotech partners across diverse programs and modalities.
- Develop mechanistic and data-driven models for tissue distribution, volume of distribution, plasma protein binding, and blood-brain barrier penetration.
- Translate complex ADMET and PK/PD science into practical, interpretable model outputs and workflows.
- Define data requirements and validation approaches to ensure models are scientifically sound.
- Leverage AI and agentic tools to automate data pipelines and streamline delivery of outputs to partners.
Requirements
- PhD in Pharmaceutical Sciences, Pharmacokinetics, Pharmacometrics, Clinical Pharmacology, Drug Metabolism, Toxicology, or a related STEM discipline.
- 7+ years of relevant experience in ADME/PKPD, Pharmacometrics, Translational Medicine, or a closely related field.
- Hands on experience with modelling platforms used in relevant fields such as SimCYP, GastroPlus, PK-Sim, NONMEM, Monolix, R, Matlab etc.
- Extensive knowledge of medicinal chemistry and/or toxicology principles
- Experience with small molecule discovery, including Beyond-Rule-of-Five and pan-modality chemotypes.
- Strong communication skills with the ability to make complex quantitative science accessible to diverse audiences.
- Track record of scientific contributions to pharmacokinetics, pharmacodynamics, ADMET, or pharmaceutical sciences.
Benefits
- eligibility to participate in a company-sponsored 401(k)
- pension
- vacation benefits
- eligibility for medical, dental, vision and prescription drug benefits
- flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- life insurance and death benefits
- certain time off and leave of absence benefits
- well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
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