About the role

Distinguished Scientist leading predictive toxicology initiatives for drug discovery at Johnson & Johnson. Collaborate with global teams to refine in vitro screening workflows and maintain toxicology expertise.

Responsibilities

Lead efforts to build and refine robust high-throughput in vitro organ specific cellular screening workflows
Serve as the liaison between High throughput screening, Data Sciences, In Silico Modeling and Preclinical Safety Teams
In collaboration with External Scientific Innovation and Business Development, evaluate external environment to identify new technologies, platforms & CROs with novel, cutting edge applications for in vitro toxicology
Partner with members of Translation Safety & Discovery, Product Development and Supply (DPDS) functional groups to oversee the conversion of mechanistic cellular, molecular & biochemical toxicology assays into high throughput predictive screening assays
Function as a key member of Global Translational Safety Team partnering with global leads to establish strategic goals and objectives
Communicate screening plans and updates to leadership and multidisciplinary teams
Maintain toxicology expertise through collaborations within TPPIT & PSTS globally, DPDS, and through organizational associations, literature reviews, continuing education, and publications.
Partner with Global Lead of Cellular & Molecular Toxicology, as well as Safety Pharmacology leads to establish strategic goals and objectives.
Identify topics appropriate for internal and external scientific publication, author scientific publications, posters and or draft documents for official communication (i.e. Contributing Scientist Reports, weight of evidence packages).

A minimum of a Ph.D. and postdoctoral work in Toxicology, Pharmacology, Biology or related field is required.
A minimum of 2-5 years postdoctoral training with a total of 12+ years of relevant work experience is required.
Demonstrated knowledge in designing and conducting mechanistic in vitro studies incorporating high throughput applications of cell-based models required.
Experience with high throughput applications of organotypic models incorporating multiple cell types including immune cells required.
Demonstrated knowledge of drug discovery and experience with drug modalities beyond small molecules required.
Advanced knowledge of cellular and molecular toxicology and demonstrated experience driving projects to completion required.
Track record of working collaboratively to solve sophisticated scientific problems required.
Experience working on & leading highly matrixed, multi-disciplinary teams required.
Experience with AI/ML and in silico toxicology modeling preferred.
Board Certification in Toxicology preferred.
Must be highly motivated, curious, and organized individual with a team-oriented mentality who enjoys working in a fast-paced, dynamic environment, and working collaboratively across functions.
Excellent written, visual, and oral communication skills.

medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance
consolidated retirement plan (pension)
savings plan (401(k))
vacation - up to 120 hours per calendar year
sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
holiday pay, including Floating Holidays - up to 13 days per calendar year
work, personal and family time - up to 40 hours per calendar year
parental leave - 480 hours within one year of the birth/adoption/foster care of a child
bereavement leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
caregiver leave - 80 hours in a 52-week rolling period
10 days volunteer leave - 32 hours per calendar year
military spouse time-off - 80 hours per calendar year