Hybrid Program Manager – Engineering Projects

at ImmunityBio, Inc.

• Job title: Program Manager – Engineering Projects
• Job type: Full Time
• Experience level: Mid level, Senior
• Salary: $95,400 - $115,000 per year
• Degree requirement: Bachelor's Degree
• Tech skills: PMP
• Location requirements: Hybrid, El Segundo, United States

About the role

• Program Manager overseeing engineering projects crucial for manufacturing at ImmunityBio. Responsible for planning, execution, and delivery of facility and engineering projects.

Responsibilities

• Owns end-to-end delivery of assigned facility, utility, and equipment projects from concept through turnover to Operations, acting as the primary point of contact for scope, schedule, budget, and quality.
• Develops and maintains integrated program plans, including scope definition, milestones, resource plans, budgets, and risk registers for facility buildouts, renovations, and equipment installations.
• Coordinates internal resources and external partners (contractors, vendors, commissioning and qualification providers) to execute the program scope in a highly regulated environment.
• Leads regular project meetings, prepares status reports, and communicates progress, risks, and mitigation strategies to stakeholders and site leadership.
• Identifies critical path activities, dependencies, and potential bottlenecks; develops and implements recovery plans as needed to maintain project commitments.
• Plans, organizes, and directs a wide variety of capital projects including new construction, facility expansions, laboratory and cleanroom buildouts, and infrastructure upgrades.
• Partners with Facilities, Manufacturing, Quality, EHS, and external design teams to ensure facility layouts and building systems (HVAC, utilities, process piping, electrical, controls) meet operational, regulatory, and safety requirements.
• Partners with multiple project teams to ensure completion of all ongoing projects.
• Ensures design and construction are aligned with cGMP requirements for biopharmaceutical operations, including controlled environments, material and personnel flows, and segregation strategies.
• Monitors construction progress, reviews field changes, and assists in resolution of site issues; evaluates and recommends approval of change orders that impact scope, cost, or schedule.
• Leads or coordinates commissioning and qualification activities for new and modified equipment, utilities, and systems in partnership with Engineering, Validation, and Quality.
• Supports development and execution of CQV deliverables (URS, design reviews, FAT/SAT, IQ/OQ/PQ protocols, summary reports) to ensure equipment is fit for intended use and compliant with regulatory expectations.
• Ensures program and project timelines account for CQV activities, documentation reviews, and regulatory/QA approvals required for GMP release.
• Drives resolution of technical and validation issues during startup and qualification, coordinating cross-functional troubleshooting and escalation as needed.
• Ensures projects are executed in compliance with applicable building and safety codes, environmental regulations, and company standards.
• Partners with EHS to plan and monitor construction safety programs and ensure contractor compliance with site safety requirements.
• Supports internal and external audits/inspections related to facilities, equipment, and validation, including preparation and presentation of project and CQV documentation.
• Develops program and project budgets and cash flow forecasts; tracks and reports capital spend against approved funding.
• Reviews and evaluates vendor and contractor proposals, scopes of work, and change orders; provides recommendations for selection and award.
• Reviews invoices in line with completion milestones and contract terms.
• Facilitates cross-functional communication and decision-making to ensure alignment between Engineering, Operations, Quality, Supply Chain, and other stakeholders.
• Escalates key issues, risks, and decisions to leadership with clear options and recommendations.
• Prepares and delivers project updates to executive and site leadership, including dashboards, presentations, and written reports.

Requirements

• Bachelor’s degree in engineering, science or relevant field required.
• 3+ years of engineering program/project management experience in biotechnology, pharmaceutical, or other regulated life sciences manufacturing environment is required.
• Experience with facility buildouts and equipment CQV strongly preferred.
• Experience leading capital or infrastructure projects involving construction, utilities, and equipment installation in cGMP or similarly regulated environments preferred.
• Experience working with cross-functional teams, external design and construction partners, and multiple stakeholders in a matrixed organization preferred.
• Hands-on experience with both traditional (Waterfall) and Agile or hybrid project management methodologies preferred.
• PMP or other project management certification preferred.

Benefits

• Medical, Dental and Vision Plan Options
• Health and Financial Wellness Programs
• Employer Assistance Program (EAP)
• Company Paid and Voluntary Life/AD&D, Short-Term and Long-Term Disability
• Healthcare and Dependent Care Flexible Spending Accounts
• 401(k) Retirement Plan with Company Match
• 529 Education Savings Program
• Voluntary Legal Services, Identity Theft Protection, Pet Insurance and Employee Discounts, Rewards and Perks
• Paid Time Off (PTO) includes: 11 Holidays
• Exempt Employees are eligible for Unlimited PTO
• Non-Exempt Employees are eligible for 10 Vacation Days, 56 Hours of Health Pay, 2 Personal Days and 1 Cultural Day