Hybrid Senior Research Scientist – Large Language Models for Genomics

Posted last month

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About the role

  • Design and implement multi-agent workflows that integrate internal foundation models (e.g., BigRNA, REPRESS, FlashRNA) and external tools to identify new biological hypotheses.
  • Develop systems that leverage Retrieval Augmented Generation (RAG) by connecting LLMs to internal scientific documents, SOPs, and structured biological databases.
  • Collaborate with the machine learning team on model distillation strategies to create smaller, faster models suitable for a real-time, interactive chat interface.
  • Build out and maintain the infrastructure for the LLM agent, including databases and model context protocol (MCP) endpoints.
  • Work closely with end-users in therapeutic design, target discovery, and experimental biology to identify key use cases, gather feedback, and rapidly iterate on the product.
  • Ensure the system is transparent and trustworthy by building "explainable AI" features that help users understand and verify the AI's outputs and decisions.

Requirements

  • MSc or PhD in Computer Science, Computational Biology, Bioinformatics, or a related field.
  • 3+ years of hands-on experience architecting and building complex applications using Large Language Models.
  • Expert knowledge of Python and modern MLOps frameworks and tools; experience with agentic frameworks like LangChain is essential.
  • Demonstrated experience in building multi-agent systems that can plan, execute tasks, and interact with external tools and APIs.
  • Familiarity with high-performance computing environments and cloud services (e.g., AWS, GCP).
  • Excellent communication skills and the ability to work effectively in a multidisciplinary team, translating the needs of biologists and drug developers into technical solutions.
  • Intellectual curiosity, critical thinking, and a commitment to innovation and scientific rigor.

Benefits

  • A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
  • Highly competitive compensation, including meaningful stock ownership.
  • Comprehensive benefits - including health, vision, and dental coverage for employees and families, employee and family assistance program.
  • Flexible work environment - including flexible hours, extended long weekends, holiday shutdown, unlimited personal days.
  • Maternity and parental leave top-up coverage, as well as new parent paid time off.
  • Focus on learning and growth for all employees - learning and development budget & lunch and learns.
  • Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development, and in Kendall Square, Cambridge, Mass. - a global center of biotechnology and life sciences.

Job title

Senior Research Scientist – Large Language Models for Genomics

Job type

Experience level

Senior

Salary

Not specified

Degree requirement

Postgraduate Degree

Location requirements

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