Principal Scientist focusing on integrating perturbation data to design new molecules that modulate disease phenotypes. Collaborating across departments to drive therapeutic discovery projects.
Responsibilities
Focus on translating biological mechanisms of disease to molecular mechanisms of therapeutics
Generate, validate, and integrate multimodal generative AIML models for the de novo design of therapeutic molecules
Guide molecular perturbation experiments that validate mechanisms of disease
Build and exploit agent-orchestrated, integrated Design-Make-Test-Analyze cycles
Identify and advocate for opportunities in scientific computation
Collaborate with external groups to develop protein engineering computational methods
Requirements
PhD or equivalent in Bioinformatics, Physics, Chemistry, Computer Science, Structural Biology, or related fields
Experience in protein structural or sequence analysis
Experience in one or more programming languages (e.g. Python)
Experience with training or applying multimodal input and output ML models
Experience to work as team lead or member; ability to work/lead effectively in a matrix environment
Experience working across scientific and technical disciplines to deliver impactful solutions
Benefits
competitive salary
annual bonus based on company performance
healthcare and wellbeing programmes
pension plan membership
shares and savings programme
flexible working arrangements
Job title
Principal Scientist, Molecular Perturbation Modeling
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