Hybrid Executive Medical Director, SERM Scientific Excellence

at GSK

• Job title: Executive Medical Director, SERM Scientific Excellence
• Job type: Full Time
• Experience level: Lead
• Salary: Not specified
• Degree requirement: Postgraduate Degree
• Location requirements: Hybrid, London, Europe

About the role

• Executive Medical Director responsible for safety evaluation and risk management for vaccines at GSK. Leading clinical safety standards and practices in early-phase and non-pivotal trials.

Responsibilities

• Lead the definition, maintenance, and implementation of standardised and compliant safety approaches for first-in-human, early-phase trials, and studies involving vulnerable populations
• Serve as the study-independent chair of the internal Safety Review Committee (iSRC), driving scientifically robust reviews and guiding the interpretation of unblinded safety data to ensure participant protection and safeguard trial integrity
• Collaborate with study teams to establish appropriate safety endpoints, monitoring and surveillance methods, risk mitigation strategies, and plans for the timely analysis of emerging safety signals
• Guide decision-making processes in critical review bodies such as Data Monitoring Committees and Dose Escalation Committees to ensure the proper escalation and response to safety concerns
• Oversee the readiness and optimisation of systems for safety data collection, reporting, and analysis throughout clinical trial preparation and execution, enabling proactive signal detection and mitigation
• Provide leadership in developing scientific capabilities within SERM teams by coaching physicians and scientists, introducing innovative analytical approaches, and fostering continuous learning and improvement
• Serve as a culture champion for high performance within Global Safety while actively contributing to strategies for the evaluation and management of urgent product safety issues

Requirements

• Medical Doctor
• Completion of a primary postgraduate clinical training, clinical residency or specialty training
• Extensive, hands-on safety and pharmacovigilance knowledge and expertise in scientific safety data analysis, interpretation, and evaluation
• Proficiency in applying frameworks for reviewing unblinded safety data with meticulous attention to study integrity
• Solid understanding in vaccinology, epidemiology, and biostatistics as applied to clinical safety analysis
• Exceptional communication skills, enabling clear and impactful presentation of complex scientific data to internal and external audiences alike
• Leadership experience in developing talent, fostering collaboration, driving change management, and cultivating a high-performing operational culture, especially in cross-functional, global environments.

Benefits

• Opportunities to grow your career
• Lead high-value projects
• Work with committed colleagues who share a clear purpose
• Encourage an inclusive culture